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Recent Publications    
"SmI2-mediated couplings of a-amino acid derivatives. Formal synthesis of (-)-pumiliotoxin 251D and (+/-)-epiquinamide" Pinho, V. D.; Procter, D. J.; Burtoloso, A. C. B. Org. Lett. 2013, in press.  
"NHC-Cu(I) Catalysed Asymmetric Conjugate Silyl Transfer to Unstaurated Lactones: Application in Kinetic Resolution" Pace, V.; Rae, J. P.; Harb. H. Y.; Procter, D. J. Chem. Commun. 2013, article on line.  
"Total synthesis of (+)-pleuromutilin" Fazakerley, N. J.; Helm, M. D.; Procter, D. J. Chem. -Eur. J. 2013, in press.  
"Dihydropyrroloindoledione-based copolymers for organic electronics" Rumer, J. W.; Dai, S-Y.; Levick, M.; Kim, Y.; Madec, M-B.; Ashraf, R. S.; Huang, Z.; Rossbauer, S.; Schroeder, B.; Biniek, L.; Watkins, S. E.; Anthopoulos, T. D.; Janssen, R. A. J.; Durrant, J. R.; Procter, D. J.; McCulloch, I. J. Mater. Chem. C 2013, 1, 2711.  
"BPTs: thiophene-flanked benzodipyrrolidone conjugated polymers for ambipolar organic transistors" Rumer, J. W.; Levick, M.; Dai, S-Y.; Rossbauer, S.; Huang, Z.; Biniek, L.; Anthopoulos, T. D.; Durrant, J. R.; Procter, D. J.; McCulloch, I. Chem. Commun. 2013, article on line.  

"Nucleophilic ortho-propargylation of aryl sulfoxides: an interrrupted Pummerer/allenyl thio-Claisen rearrangement sequence" Eberhardt, A. J.; Procter, D. J. Angew. Chem. Int. Ed. 2013, 52, 4008.

 
"Synthesis of two dihydropyrroloindoledione-based copolymers for organic electronics" Rumer, J. W.; Dai, Sheng-Yao; Levick, M.; Biniek, L.; Procter, D. J.; McCulloch, I. J. Polym. Sci. A Polym. Chem. 2013, 51, 1285.  

"Phase Tag-Assisted Synthesis of Benzo[b]carbazole End-Capped Oligothiophenes" Levick, M. T.; Coote, S. C.; Grace, I.; Lambert, C.; Turner, M. L.; Procter, D. J. Org. Lett. 2012, 14, 5744  
"Beyond Samarium Diiodide: Vistas in Reductive Chemistry Mediated by Lanthanides(II)" Szostak, M.; Procter, D. J. Angew. Chem. Int. Ed. 2012, 51, 9238.  

"Lactone radical cyclizations and cyclization cascades mediated by SmI2–H2O" Parmar, D.; Matsubara, H.; Price, K.; Spain, M.; Procter, D. J. J. Am. Chem. Soc. 2012, 134, 12751.  

"Recent advances in the chemistry of SmI2–H2O" Sautier, B.; Procter, D. J. Chimia 2012, 66, 399.

Invited contribution to Special Issue. Selected for Cover Art

 

 

"A General Electron Transfer Reduction of Lactones Using SmI2–H2O" Szostak, M.; Collins, K. D.; Fazakerley, N. J.; Spain, M.; Procter, D. J. Org. Biomol. Chem. 2012, 10, 5820.

Invited contribution to "Organic & Biomolecular Chemistry 10th Anniversary" Collection.

 
"Selective synthesis of 3-hydroxy acids from Meldrum’s acids using SmI2-H2O" Szostak, M.; Spain, M.; Procter, D. J. Nat. Protocol 2012, 7, 970.  

"Preparation of Samarium(II) Iodide: Quantitative Evaluation of the Effect of Water, Oxygen, and Peroxide Content, Preparative Methods, and the Activation of Samarium Metal" Szostak, M.; Spain, M.; Procter, D. J. J. Org. Chem. 2012, 77, 3049.

 
"Electron transfer reduction of carboxylic acids using SmI2-H2O-Et3N" Szostak, M.; Spain, M.; Procter, D. J. Org. Lett. 2012, 14, 840.  
"SmI2-Mediated Carbonyl-Alkene Couplings for the Synthesis of Small Carbocyclic Rings" Harb, Y. H.; Procter, D. J. Synlett 2012, 23, 6.  
"Selective Reductive Transformations Using Samarium Diiodide-Water" Szostak, M.; Spain, M.; Parmar, D.; Procter, D. J. Chem Commun. 2012, 48, 330.  
"Radical Cyclization Cascades of Unsaturated Meldrum's Acid Derivatives" Sautier, B.; Lyons, S. E.; Webb, M. R.; Procter, D. J. Org. Lett. 2012, 14, 146.  

"Nucleophilic Ortho Allylation of Aryl and
Heteroaryl Sulfoxides" Eberhart, A. J.; Imbriglio, J. E.; Procter, D. J. Org. Lett. 2011, 13, 5882.

 

"Synthesis of the ABH rings of ecteinascidin 597 using a connective Pummerer-type cyclisation" Smith, L. H. S.; Nguyen, T. T.; Sneddon, H. F.; Procter, D. J. Chem. Commun. 2011, 47, 10821.

 
"Electron transfer reduction of unactivated esters using SmI2-H2O" Szostak, M.; Spain, M.; Procter, D. J. Chem. Commun. 2011, 47, 10254.  

 

 

"Concise Syntheses of Strychnine and Englerin A: the Power of Reductive Cyclizations Triggered by Samarium Iodide for the Rapid Assembly of Old and New Targets" Szostak, M.; Procter, D. J. Angew. Chem. Int. Ed. 2011, 50, 2.  

 

"Exploiting Sm(II) and Sm(III) in SmI2-initiated reaction cascades: application in a tag removal-cyclisation approach to spirooxindole scaffolds" Coote, S. C.; Quenum S.; Procter , D. J. Org. Biomol. Chem. 2011, 9, 5104.  

 

“Organic Synthesis Using Samarium Diiodide” Coote, S. C.; Flowers II, R. A.; Skrydstrup, T.; Procter, D. J. in Encyclopedia of Radicals in Chemistry, Biology and Materials 2012, John Wiley & Sons, Ltd.    
"Reductive Cyclization Cascades of Lactones Using SmI2–H2O" Parmar, D.; Price, K.; Spain, M.; Matsubara, H.;Bradley, P. A.; Procter, D. J. J. Am. Chem. Soc. 2011, 133, 2418.
 

 

 

"A stereoselective, Sm(II)–mediated approach to decorated cis–hydrindanes: synthetic studies on faurinone and pleuromutilin" Findley, T. J. K.; Sucunza, D.; Miller, L. C.; Helm, M. D.; Helliwell, M.; Davies, D. T.; Procter, D. J. Org. Biomol. Chem. 2011, 9, 2433.

Invited contribution to the Athel Beckwith Special issue.

 

"Product Class 17: Acyclic Hemiacetals, Lactols, and Carbonyl Hydrates" Coote, S. C.; Smith, L. H. S.; Procter, D. J. Science of Synthesis Section 29.17, Thieme, Volume Update Editor, Procter, D. J. 2010, 417.

Invited Volume Update Editor

   

 

"Product Class 18: 1,1–Diacyloxy compounds" Smith, L. H. S.; Coote, S. C.; Procter, D. J. Science of Synthesis Section 29.18, Thieme, Volume Update Editor, Procter, D. J. 2010, 475.

Invited Volume Update Editor

   
"SmI2–mediated radical cyclizations directed by a C−Si bond" Harb, H. Y.; Collins, K. D.; Garcia Altur, J. V.; Bowker, S.; Campbell, L.; Procter, D. J. Org. Lett. 2010, 12, 5446.  

 

 

 

"Dynamic Ligand Exchange in Reactions of Samarium Diiodide" Sadasivam, D. V.; Teprovich Jr, J. A.; Procter, D. J.; Flowers II, R. A. Org. Lett. 2010, 12, 4140.

 

 

 

 

“Selective reductions of cyclic 1,3-diesters using SmI2 and H2O” Collins, K. D.; Oliveira, J. M.; Guazzelli, G.; Sautier, B.; De Grazia, S.; Matsubara, H.; Helliwell, M.; Procter, D. J. Chem. –Eur. J. 2010, 16, 10240.  

 

 

“A Stereoselective Cyclization Cascade Mediated by SmI2-H2O: Synthetic Studies towards Stolonidiol” Baker, T. M.; Sloan, L. A.; Choudhury, L. H.; Murai, M.; Procter, D. J. Tetrahedron: Asymmetry 2010, 21, 1246.

Invited contribution to the Henri Kagan Special issue.

 

 

 

"Beyond the Pummerer Reaction: Recent Developments in Thionium Ion Chemistry" Smith, L. H. S.; Coote, S. C.; Sneddon, H. F.; Procter, D. J. Angew. Chem. Int. Ed. 2010, 49, 5832.  

 

 

 

"Organic Synthesis using Samarium Diiodide: A Practical Guide" Procter, D. J.; Flowers, R. A., II; Skrydstrup, T. RSC Publishing 2009.

 

   
"A dialdehyde cyclization cascade in an approach to pleuromutilin" Helm, M. D.; Da Silva, M.; Sucunza, D.; Findley, T. J. K.; Procter, D. J. Angew. Chem. Int. Ed. 2009, 48, 9315.  

 

 

 

"SmI2–mediated dialdehyde ‘radical then aldol’ cyclization cascades: a feasibility study" Helm, M. D.; Da Silva, M.; Sucunza, D.; Helliwell,M.; Procter, D. J. Tetrahedron 2009, 65, 10816.

Special issue, "Electron transfer reagents in organic synthesis". Edited by D. J. Procter and R. A. Flowers, II

 

 
"Studies on the mechanism, selectivity and synthetic utility of lactone reduction using SmI2 and H2O" Parmar, D.; Duffy, L. A.; Sadasivam, D. V.; Matsubara, H.; Bradley, P. A.; Flowers II, R. A.; Procter, D. J. J. Am. Chem. Soc. 2009, 131, 15467.  

 

“Linker units cleaved by radical processes” Guazzelli, G.; Miller, M.; Procter, D. J. In Linker Strategies In Solid–Phase Organic Synthesis, Ed. Peter J. H. Scott, Wiley, 2009, Chapter 15, 419.

Invited contribution

   

 

"Selective reductions of cyclic 1,3–diesters using SmI2 and H2O" Guazzelli, G.; De Grazia, S.; Collins, K. D.; Matsubara, H.; Spain, M.; Procter, D. J. J. Am. Chem. Soc. 2009, 131, 7214.

 

 

 

 

"Intramolecular aryl transfer to thionium ions in an approach to α-arylacetamides" Ovens, C.;, Vogel, J. C.; Martin, N. G.; Procter, D. J. Chem. Commun. 2009, 3101.  

 

 

"SmI2–mediated dialdehyde cyclization cascades" Helm, M. D.; Sucunza, D.; Da Silva, M.; Helliwell, M.; Procter, D. J. Tetrahedron Lett. 2009, 50, 3224.

Invited contribution to the 50th Anniversary special issue

 

 

 

"Formation of N–heterocycles by the reaction of thiols with glyoxamides: Exploring a connective Pummerer-type cyclisation” Miller, M.; Vogel, J.; Tsang, W.; Merrit, A.; Procter, D. J. Org. Biomol. Chem. 2009, 7, 589.

 

 

 

 

“An asymmetric, SmI2–mediated approach to g–butryolactones using a new, fluorous-tagged auxiliary“ Vogel, J.; Butler, R.; Procter. D. J. Tetrahedron 2008, 64, 11876.

Invited contribution to a special issue “Modern Radical Methodology In Organic Synthesis”

 

 

 

 

“A samarium(II)–mediated, stereoselective cyclization for the synthesis of spirocyclic lactams” Guazzelli, G.; Duffy, L. A. Procter, D. J. Org. Lett. 2008, 10, 4291.  

 

 

“A flexible, stereoselective approach to the decorated cis–hydrindane skeleton: synthesis of the proposed structure of faurinone" Findley, T. J. K.; Sucunza, D.; Miller, L. C.; Davies, D. T.; Procter, D. J. Chem.–Eur. J. 2008, 14, 6862.  

 

 

“Synthesis and reactions of the pestalotiopsin skeleton” Baker, T. M.; Edmonds, D. J.; Hamilton, D.; O’Brien, C. J.; Procter, D. J. Angew. Chem. Int. Ed. 2008, 47, 5631.  

 

 

“Total Synthesis of (-)-Martinellic Acid via Radical Addition-Cyclization-Elimination Reaction” Shirai, A.; Miyata, O.; Tohnai, N.; Miyata, M.; Naito, T.; Procter, D. J.; Sucunza, D. J. Org. Chem. 2008, 73, 4464.

 

   
“Methanolysis of Tetraphenylborate (BPh4-) as a reaction unit in halotris(2,4-petadianato) complexes of Zr(IV) and Hf(IV)” Mlondo, S. N.; O’Brien, P.; Thomas, P. J.; Helliwell, M.; Raftery, J.; Procter, D. J. Chem. Commun. 2008, 2456.    
“A dearomatizing, thionium ion cyclization for the synthesis of functionalized, azaspirocyclic cyclohexadienones” Ovens, C.; Martin, N. G.; Procter, D. J. Org. Lett. 2008, 10, 1441.  

 

 

“Samarium(II)–mediated linker cleavage–cyclization in fluorous synthesis: reactions of samarium enolates” James, K. M.; Willetts, N.; Procter, D. J. Org. Lett. 2008, 10, 1203.  

 

 

“A Ring Size-Selective Reduction of Lactones Using SmI2 and H2O” Duffy, L. A.; Matsubara, H.; Procter, D. J. J. Am. Chem. Soc. 2008, 130, 1136.

Highlighted in Org. Proc. Res. Dev. 2008, 12, 358-368.

 

 

 

“Samarium enolates and their application in organic synthesis” Rudkin, I. M.; Miller, L. C.; Procter, D. J. Organomet. Chem. 2008, 34, 19.    
"Application of a Sm(II)-mediated spirocyclization in an asymmetric approach to the cyclopentanol motif of stolonidiol" Sloan, L. A.; Baker, T.; Macdonald, S. J. F.; Procter, D. J. Synlett 2007, 3155.  

 

 

“Synthesis and evaluation of a new polymer–supported pseudoephedrine auxiliary for asymmetric alkylations on solid phase” McGhee, A. M.; Kizirian, J–C.; Procter, D. J. Org. Biomol. Chem. 2007, 5, 1021.  

 

 

"A Fluorous, Pummerer Cyclative–Capture Strategy for the Synthesis of N–Heterocycles" McAllister, L. A.; McCormick, R. A.; James, K. M.; Brand, S.; Willetts, N.; Procter, D. J. Chem. Eur J. 2007, 13, 1032.  

 

 

"Exploring a new, connective Pummerer reaction: formation of oxindoles by the reaction of thiols with glyoxamides" Miller, M.; Tsang, W.; Merritt, A.; Procter, D. J. Chem. Commun. 2007, 498.  

 

 

"Solid Phase Approaches to N-heterocycles using a sulfur linker cleaved using SmI2" McAllister, L. A.; Turner, K. L.; Brand, S.; Stefaniak, M.; Procter, D. J. J. Org. Chem. 2006, 71, 6497.  

 

 

“Lanthanide Reagents in Solid Phase Synthesis” Sloan, L. A.; Procter, D. J. Chem. Soc. Rev. 2006, 35, 1221.  

 

 

“Developing New Cleavage Strategies in a Fluorous Phase Pummerer Cyclative–Capture Approach for the Synthesis of N–Heterocycles” McCormick, R. A.; James, K. M.; Willetts, N.; Procter, D. J. QSAR Comb. Sci. 2006, 25, 709.

Invited contribution to a special issue on fluorous chemistry

 

   

"Radical Chemistry on Solid Support" McGhee, A. M. and Procter, D. J. Topp. Curr. Chem. 2006, 264, 93.

Invited contribution to a special issue on radical chemistry

   
"A solid phase approach to tetrahydroquinolones using a sulfur linker cleaved by SmI2" Turner, K. L.; Baker, T. M.; Islam, S.; Procter, D. J.; Stefaniak, M. Org. Lett. 2006, 8, 329.  

 

 

"Sulfide and selenide–base linkers in phase tag–assisted synthesis" McAllister, L. A.; McCormick, R. A.; Procter, D. J. Tetrahedron 2005, 61, 11527.  

 

 

“Evaluation of a new linker system cleaved using samarium(II) iodide. Application in the solid phase synthesis of carbonyl compounds" F. McKerlie, F.; Rudkin, I. M.; Wynne, G.; and Procter, D. J. Org. Biomol. Chem. 2005, 3, 2805.  

 

 

"A fluorous-phase Pummerer cyclative-capture strategy for the synthesis of nitrogen heterocycles" McAllister, L. A.; McCormick, R. A.; Brand, S.; Procter, D. J. Angew. Chem. Int. Ed. 2005, 44, 452.  

 

 

“The samarium(II)-mediated intermolecular couplings of ketones and b-alkoxyacrylates: A short asymmetric synthesis of an antifungal g-butyrolactone” Kerrigan, N. J.; Upadhyay, T.; Procter, D. J. Tetrahedron Lett. 2004, 45, 9087.  

 

 

“Development of a solid-phase 'asymmetric resin-capture - release' process: Application of an ephedrine chiral resin in an approach to g-butyrolactones” Kerrigan, N. J.; Hutchison, P. C.; Heightman, T. D.; Procter, D. J. Org. Biomol. Chem. 2004, 2476.

 

 

 

"Samarium(II) iodide-mediated cyclizations in natural product synthesis" Edmonds, D. J.; Johnston, D.; Procter, D. J. Chem. Rev. 2004, 104, 3371.  

 

 

“Application of a recyclable pseudoephedrine resin in asymmetric alkylations on solid phase”
Hutchison, P. C.; Heightman, T. D.; Procter, D. J. J. Org. Chem. 2004, 790.
 

 

 

"Switching between novel samarium(II)-mediated cyclizations by a simple change in alcohol cosolvent”
Hutton, T. K.; Muir, K. W.; Procter, D. J.
Org. Lett. 2003, 5, 4811.
 

 

 

"The first Pummerer cyclisations on solid phase. Convenient construction of oxindoles enabled by a sulfur-link to resin"
McAllister, L. A.; Brand, S.; de Gentile, R.; Procter, D. J. Chem. Commun. 2003, 2380.
 

 

 

"Application of an ephedrine chiral linker in a solid-phase, 'asymmetric catch-release' approach to g-butyrolactones"
Kerrigan, N. J.; Hutchison, P. C.; Heightman, T. D.; Procter, D. J. Chem. Commun. 2003, 1402.
 

 

 

"The Remarkable Effect of co-solvent on a Samarium(II)-mediated 4-exo-trig Cyclisation: Further Synthetic Studies on Pestalotiopsin A"
Edmonds, D. J.; Muir, K. W.; Procter, D. J. J. Org. Chem. 2003, 68 ,3190.
 

 

 

"The first synthetic studies on pestalotiopsin A. A stereocontrolled approach to the functionalised bicyclic core" Johnston, D.; Couché, E.; Edmonds, D. J.; Muir, K.; Procter, D. J. Org. Biomol. Chem. 2003, 1, 328.  

 

 

"Evaluation of a pseudoephedrine linker for asymmetric alkylations on solid phase" Hutchison, P. C.; Heightman, T. D.; Procter, D. J. Org. Lett. 2002, 4, 4583.  

 

 

"Samarium(II)-Mediated Reactions of g,d -Unsaturated Ketones. Cyclization and Fragmentation Processes" Hutton, T. K.; Muir, K.; Procter, D. J. Org. Lett. 2002, ,4, 2345.  

 

 

"Reduction of a-aryloxy carbonyl compounds with samarium(II) iodide. A new traceless linker for the solid phase synthesis of carbonyl compounds"
McKerlie, F.; Procter, D. J.; Wynne, G. Chem. Commun. 2002, 584.

 

 

 

 

"Samarium(II)-Mediated 4-exo-trig cyclization. A Stereocontrolled Approach to the Core of Pestalotiopsin A" Johnston, D.; Francon, N.; Edmonds, D. J.; Procter, D. J. Org. Lett. 2001, 3, 2001.

 

 

 

 

“The synthesis of thiols, selenols, sulfides, selenides, sulfoxides, selenoxides, sulfones and selenones” Procter, D. J. J. Chem. Soc., Perkin Trans. 1 2001, 335.    
"Convenient preparation of ytterbium(III) chalcogenolate complexes by insertion of ytterbium into chalcogen-chalcogen bonds. Application in the ring-opening of epoxides" Dowsland, J.; McKerlie, F.; Procter, D. J. Tetrahedron Lett. 2000, 41, 4923.  

 

 

"Samarium(II)-mediated 4-exo-trig cyclisations of unsaturated aldehydes. A stereoselective approach to functionalised cyclobutanols" Johnston, D.; McCusker, C. F.; Muir, K.; Procter, D. J. J. Chem. Soc., Perkin Trans. 1 2000, 681.

 

 

 

 

“The synthesis of thiols, selenols, sulfides, selenides, sulfoxides, selenoxides, sulfones and selenones” Procter, D. J. J. Chem. Soc., Perkin Trans. 1 2000, 835.

 

   
“The synthesis of thiols, selenols, sulfides, selenides, sulfoxides, selenoxides, sulfones and selenones” Procter, D. J. J. Chem. Soc., Perkin Trans. 1  1999, 641.  

 

 

 

“Samarium(II)-Mediated 4-exo trig Ketyl-Olefin Cyclisation of Unsaturated Aldehydes. A General, Stereoselective Synthesis of Functionalised Cyclobutanols” Johnston, D.; McCusker, C. M.; Procter, D. J. Tetrahedron Lett. 1999 , 40, 4913.  

 

 

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